The Association Between Hba1c Levels And Cognitive Function In Geriatric Patients With Type 2 Diabetes Mellitus

Parengkuan, Irene Lingkan, Oeylex, Celine Elvirenov and Muliono, Ari Christy (2024) The Association Between Hba1c Levels And Cognitive Function In Geriatric Patients With Type 2 Diabetes Mellitus. Journal of Widya Medika Junior, 6 (4). pp. 299-308. ISSN 2565-1409

	Text (The Association Between Hba1c Levels And Cognitive Function In Geriatric Patients With Type 2 Diabetes Mellitus) 2-The_association_between_.pdf Download (223kB)
	Text (The Association Between Hba1c Levels And Cognitive Function In Geriatric Patients With Type 2 Diabetes Mellitus) 2-The_association_between_hasil_cek_similarity_.pdf Download (2MB)

Abstract

Type 2 diabetes mellitus (T2DM) is a significant global health concern, particularly in Indonesia. Recent studies suggest a link between T2DM and increased risk of cognitive impairment. However, the relationship between glycaemic control, as measured by HbA1c levels, and cognitive function in elderly diabetic patients remains unclear and requires further investigation. Objective: To investigate the association between HbA1c levels and cognitive impairment in geriatric patients with T2DM. Method: This observational analytic study with a cross-sectional approach was conducted at the Internal Medicine Clinic of Gotong Royong Hospital in Surabaya, Indonesia. Thirty-six geriatric T2DM patients were recruited using consecutive sampling. HbA1c levels were obtained from medical records, and cognitive function was assessed using the Montreal Cognitive Assessment-Indonesian Version (MoCA-INA). Data were analyzed using SPSS software, including normality tests and Spearman correlation analysis. Result: The majority of participants were female (77.8%) and aged 60-69 years (47.2%). Eleven participants (50%) of the 22 T2DM geriatric patients with good-controlled HbA1c levels had poor cognitive function (scores < 26). Meanwhile, among the 14 participants with poorly controlled HbA1c levels, 11 (78.6%) had poor cognitive function, and only 3 (21.4%) maintained good cognitive function. A significant negative correlation was found between HbA1c levels and MoCA-INA scores (p=0.013, r=-0.410), indicating that higher HbA1c levels were associated with lower cognitive function scores. Conclusion: This study demonstrates a significant relationship between HbA1c levels and cognitive function in elderly T2DM patients. Poor glycemic control is associated with a higher likelihood of cognitive impairment. These findings emphasize the importance of maintaining good glucose management to potentially prevent cognitive decline in this population. Further research with larger sample sizes and longitudinal designs is recommended to elucidate this relationship and its clinical implications.

Item Type:	Article
Uncontrolled Keywords:	Type 2 Diabetes Mellitus, Geriatric, HbA1C, Cognitive function
Subjects:	Medicine
Divisions:	Journal Publication
Depositing User:	F.X. Hadi
Date Deposited:	09 Dec 2024 07:20
Last Modified:	03 Feb 2025 08:54
URI:	https://repository.ukwms.ac.id/id/eprint/41276

Actions (login required)

View Item