Investigating chemical changes during snakefruit and black tea kombucha fermentation and the associated immunomodulatory activity In Salmonella typhi infected mice

Zubaidah, Elok, Valencia, Vania, Rifa'i, Muhaimin, Srianta, Ignatius and Tewfik, Ihab Investigating chemical changes during snakefruit and black tea kombucha fermentation and the associated immunomodulatory activity In Salmonella typhi infected mice. Potravinarstvo Slovak Journal of Food Sciences, 14. pp. 995-1000. ISSN 1337-0960

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Abstract

This study uncovered the chemical changes during kombucha's fermentation process and revealed the associated immunomodulatory activity in Salmonella typhi-infected mice. The snake fruit juice and black tea extract were processed into kombucha (a beverage known for its health benefits) by fermentation with SCOBY culture at room temperature for 14 days. Snake fruit kombucha showed high changes in fermentation parameters (total acidity, pH, and total sugar), as well as bioactive compounds and antioxidant activity. Salmonella typhi demonstrated a reduction in the population of CD8+TNFα+ and CD4+IFNγ+ of infected experimental animals. Both snake fruit kombucha and black tea kombucha have the potential to be utilized as an immunomodulator to circumvent unstable conditions of the immune system caused by Salmonella typhi. Black tea kombucha and snake fruit kombucha cancan raise the production of CD8+TNFα+ and CD4+IFNγ+ in mice infected with Salmonella typhi. In the group of normal mice, black tea and snake fruit kombucha were able to lower down the production of CD8+TNFα+, which is a potent mechanism to modulate the immune system. Further research is required to highlight the mechanism and role of black tea kombucha and snake fruit kombucha in the immune response that modulates and treats infection by Salmonella typhi.

Item Type:	Article
Uncontrolled Keywords:	kombucha; snake fruit; black tea; immunomodulator; Salmonella typhi
Subjects:	Agriculture and Food Technology
Divisions:	Journal Publication
Depositing User:	Ignatius Srianta
Date Deposited:	29 Oct 2023 03:16
Last Modified:	02 Nov 2023 06:44
URI:	http://repository.ukwms.ac.id/id/eprint/37140

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