Widyawati, Paini Sri, Werdani, Yesiana Dwi Wahyu, Setyokusumo, Christine and Kartikasari, Adriana (2017) IN VITRO ANTIOXIDANT CAPACITIES AND ANTIDIABETIC PROPERTIES OF PLUCHEA LEAVES AND GREEN TEA MIXTURES AT VARIOUS PROPORTIONS. International Journal of Pharmacy and Pharmaceutical Sciences, 9 (8). pp. 203-208. ISSN 0975-1491
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Abstract
Objective: This study was done to determine the effect of pluchea leaves and green tea proportion to antioxidant and antidiabetic properties. Methods: The research used a single factor randomized block design. Research factor was pluchea and green tea proportion, including 100:0; 75:25; 50:50; 25:75; and 0:100% (w/w). Each of it was repeated five times. The parameters observed in this study were phytochemical compounds, total phenol, total flavonoids, free radical DPPH scavenging activity, iron reducing power, alpha amylase and alpha glycosidase inhibition activities. The data were statistically analyzed using ANOVA (Analysis of Variance) at α = 5%, if the analysis showed a significant effect then it was continued with Duncan's Multiple Range Test. Results: The phytochemical compounds containing in pluchea leaves and green tea were alkaloids, flavonoid, phenolic, saponin, tannin, triterpenoid, sterol, and cardiac glycoside. The qualitative assay of phytochemical compounds from aqueous extract was different pattern with total phenolic content (TPC) and total flavonoid content (TFC), especially at 75:25; 50:50 and 25:75 % (w/w) from pluchea leaves and green tea proportions. TPC and TFC at 50:50% (w/w) proportion were the highest, it proposed that there was interaction between bioactive compounds of pluchea leaves and green tea. TPC and TFC were correlated with free radical DPPH scavenging activity, iron reducing power and alpha glycosidase inhibition activity, but the alpha amylase inhibition activity had the different graph pattern with the TPC and TFC. Conclusion: The antioxidant capacity of pluchea leaves and green tea mixture at various proportions had the graph pattern similar to the alpha glycosidase inhibitory activity and different with the alpha amylase inhibitory activity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Pluchea leaves, green tea, antioxidant, and antidiabetic |
| Subjects: | Agriculture and Food Technology |
| Divisions: | Book > Food Technology Study Program |
| Depositing User: | Paini Sri Widyawati |
| Date Deposited: | 29 Oct 2023 03:46 |
| Last Modified: | 29 Oct 2023 03:46 |
| URI: | http://repository.ukwms.ac.id/id/eprint/14396 |
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